SALK'S VACCINE : Almost two years was spent developing Salk's polio vaccine. Throughout this time he developed several vaccines, each being made a different way. Several different methods were used on growing the virus . Several different ways of killing the virus. He also tried different combinations of killed viruses. Salk tested all the vaccines on monkeys. All of Salk's hard work and research came together on March 26, 1953 when he announced that he had successfully tested a vaccine against polio. The vaccine was made of killed viruses. Do to the fact that the viruses were killed there was less of a chance for the patients that were given the vaccine to get polio from it.
First taken image of the polioviruses.
Salk's version of the Polio Vaccine
SABIN'S VACCINE : Like Salk, Sabin wanted to develop a safe and effective polio vaccine. But, Sabin disagreed with Salk about using and injecting a "killed" virus. Sabin believed that long-term immunity could only be achieved with a live virus. In 1962, Sabin's vaccine was introduced in the United States. Sabin's vaccine was an oral, live virus vaccine. Sabin claimed that his vaccine had three major advantages. The first was that it was easier and less expensive to make. The second was that it could be taken by mouth in a liquid dropped on a sugar cube. The third was that it provided a stronger, longer lasting immunity. Gradually, the Salk vaccine was being given less and less.